Summary
This multinational GBD study synthesises cardiovascular disease burden across 18 disease entities and 15 risk factors globally from 1990–2022, employing standardised metrics to quantify morbidity, mortality and disability. The work represents a collaborative effort of >10,000 researchers and provides a comprehensive epidemiological reference for clinicians, health systems and policymakers. Findings are organised by GBD region to facilitate comparative health burden assessment and priority-setting.
UK applicability
The UK, as a high-income nation with established cardiovascular surveillance infrastructure, can benchmark its CVD burden and risk factor attribution against global and regional comparators. Results may inform National Health Service prevention strategies and health inequality assessments, particularly regarding dietary risk factor burden.
Key measures
Prevalence, cause-specific mortality rate (CSMR), years of life lost (YLLs), years lived with disability (YLDs), disability-adjusted life years (DALYs)
Outcomes reported
The study quantified the global burden of 18 cardiovascular diseases and 15 associated risk factors (including dietary risks) across GBD regions using standardised metrics including prevalence, cause-specific mortality, years of life lost, years lived with disability, and disability-adjusted life years. Data span 1990–2022 and are stratified by region to enable comparison across health systems and policy contexts.
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