Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

Contemporary Presentation and Management of Valvular Heart Disease

Bernard Iung, Victoria Delgado, Raphael Rosenhek, Susanna Price, Bernard Prendergast, Olaf Wendler, Michele De Bonis, Christophe Tribouilloy, Arturo Evangelista, Alexander Bogachev‐Prokophiev, Astrid Apor, Hüseyin Ince, Cécile Laroche, Bogdan A. Popescu, Luc Piérard, Michael Haude, Gerhard Hindricks, Frank Ruschitzka, Stefan Windecker, Jeroen J. Bax, Aldo P. Maggioni, Alec Vahanian, And the EORP VHD II Investigators, Artan Goda, Julia Mascherbauer, Fuad Samadov, Agnes Pasquet, Katerina Linhartova, Nikolaj Ihlemann, Magdy Abdelhamid, Antti Saraste, Christophe Tribouilloy, Elizabeta Srbinovska Kostovska, Gani Bajraktari, Erkin Mirrakhimov, Andrejs Erglis, Vaida Mizariene, Daniela Cassar, Victoria Delgado, Lidia Tomkiewicz-Pajak, Regina Ribeiras, Branko Beleslin, Iveta Simkova, Arturo Evangelista, Sait Mesut Dogan, Shelley Rahman-Haley

Circulation · 2019

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Summary

This prospective observational survey enrolled 7,247 patients with severe native valvular heart disease or previous valvular intervention across 222 centres in 28 European countries during 2017. The study found aortic stenosis was the most common severe valve lesion (41.2% of native VHD cases), and that clinical decision-making for intervention aligned with Class I guideline recommendations in 68.5–79.4% of symptomatic patients depending on valve type, suggesting variable but substantial guideline adherence across European practice.

UK applicability

As a European multi-country observational study, findings are directly applicable to UK valvular heart disease management and guideline concordance. The study provides benchmarking data relevant to NHS cardiology services and may inform quality improvement initiatives around guideline-concordant care pathways in UK hospitals.

Key measures

Prevalence of valve disease types (aortic stenosis, aortic regurgitation, mitral stenosis, mitral regurgitation, multiple left-sided VHD, right-sided VHD); proportion of patients undergoing intervention; concordance with Class I guideline recommendations by valve type; patient demographics (age, sex, hospitalization status)

Outcomes reported

The study documented the prevalence and management patterns of severe native valvular heart disease across 28 European countries, and assessed concordance between clinical interventions and Class I guideline recommendations. Valvular interventions were performed or scheduled in 63.8% of patients with native VHD, with concordance rates ranging from 68.5% to 79.4% across different valve pathologies.

Theme
General food systems / other
Subject
Other / interdisciplinary
Study type
Research
Study design
Observational cohort
Source type
Peer-reviewed study
Status
Published
Geography
Europe
System type
Human clinical
DOI
10.1161/circulationaha.119.041080
Catalogue ID
SNmojad8q1-ge639q

Topic tags

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