Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

Biodegradable Implantable Sensors: Materials Design, Fabrication, and Applications

Nureddin Ashammakhi, Ana López Hernández, Bige Deniz Unluturk, Sergio Quintero, Natan Roberto de Barros, Ehsanul Hoque Apu, Abdullah Bin Shams, Serge Ostrovidov, Jinxing Li, Christopher H. Contag, Antoinette S. Gomes, Miguel Holgado

Advanced Functional Materials · 2021

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Summary

This narrative review synthesises recent advances in biodegradable implantable sensor technology, examining how progress in materials science has enabled the fabrication of fully biodegradable sensor components that eliminate the need for surgical removal. The authors critically evaluate the performance of biodegradable sensors relative to commercial non-degradable alternatives, whilst identifying key design constraints—including implant miniaturisation, power management, and material selection—that currently limit clinical applications. The review highlights significant potential for personalised medicine applications, particularly in sensitive tissue environments such as the central nervous system, whilst noting that the field remains in early development.

UK applicability

This review's findings on biodegradable sensor technology have potential applicability to UK clinical practice and precision medicine initiatives, particularly for monitoring applications in sensitive tissues. However, the work is primarily relevant to biomedical and materials science research; direct application to UK farming, soil health, or food systems is not evident.

Key measures

Sensor accuracy, reliability, material biodegradability, implant size, power consumption, tissue compatibility

Outcomes reported

The paper reviews recent advances in biodegradable sensor materials, design, and fabrication that enable real-time monitoring of diseases and therapies without requiring removal procedures. It evaluates the performance characteristics, constraints, and future prospects of biodegradable implantable sensors compared to conventional non-degradable devices.

Theme
Measurement & metrics
Subject
Other / interdisciplinary
Study type
Narrative Review
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
System type
Laboratory / in vitro
DOI
10.1002/adfm.202104149
Catalogue ID
SNmojbipg9-1y2mq9

Topic tags

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