Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

Comparison of the prevalence of 21 GLIM phenotypic and etiologic criteria combinations and association with 30-day outcomes in people with cancer: A retrospective observational study

Nicole Kiss, Belinda Steer, M.A.E. de van der Schueren, Jenelle Loeliger, Roohallah Alizadehsani, Lara Edbrooke, Irene Deftereos, Erin Laing, Abbas Khosravi

Clinical Nutrition · 2022

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Summary

This retrospective observational study examined the distribution of 21 different combinations of GLIM malnutrition criteria phenotypes and aetiologies in a cancer population, and their association with short-term clinical outcomes at 30 days. The work appears to contribute to validation of the GLIM framework as a standardised malnutrition assessment tool in oncology, exploring whether specific criterion combinations predict adverse clinical events more strongly than others. The findings may support refinement of malnutrition screening and intervention prioritisation in cancer care settings.

UK applicability

This research is directly applicable to UK oncology and nutrition practice, as GLIM is internationally adopted and cancer-related malnutrition is a significant concern in UK hospital and community settings. The 30-day outcome focus aligns with NHS quality metrics and could inform malnutrition risk stratification in UK cancer centres.

Key measures

Prevalence of GLIM malnutrition phenotypic and aetiologic criterion combinations; 30-day clinical outcomes (mortality, morbidity, complications)

Outcomes reported

The study assessed the prevalence of 21 combinations of Global Leadership Initiative on Malnutrition (GLIM) phenotypic and aetiologic criteria in people with cancer, and evaluated their association with 30-day mortality or morbidity outcomes.

Theme
Nutrition & health
Subject
Micronutrients & dietary adequacy
Study type
Research
Study design
Retrospective observational cohort
Source type
Peer-reviewed study
Status
Published
System type
Human clinical
DOI
10.1016/j.clnu.2022.03.024
Catalogue ID
SNmojg03sj-zbqwe6

Topic tags

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