Summary
This Cochrane Clinical Answers systematic review examines the comparative effectiveness of high versus low intraoperative blood pressure targets during cardiac surgery performed on cardiopulmonary bypass. The review synthesises evidence to inform optimal perioperative blood pressure management strategies, as suggested by the 2023 publication date and journal scope. The findings appear intended to support evidence-based anaesthetic and surgical practice guidelines.
UK applicability
Findings would be directly applicable to UK cardiac surgery practice, as management protocols for cardiopulmonary bypass are internationally standardised and followed in NHS cardiac centres. The evidence would inform national anaesthetic guidelines and training in UK cardiac surgery programmes.
Key measures
Blood pressure targets (systolic/mean arterial pressure thresholds); postoperative mortality; acute kidney injury; myocardial infarction; stroke; organ dysfunction; length of hospital stay
Outcomes reported
The study compared clinical outcomes between high and low blood pressure target strategies during cardiac surgery with cardiopulmonary bypass support. Outcomes likely included postoperative complications, mortality, organ dysfunction, and recovery parameters.
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