Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Bilateral versus Single Internal-Thoracic-Artery Grafts at 10 Years

David P. Taggart, Umberto Benedetto, Stephen Gerry, Douglas G. Altman, Alastair Gray, Belinda Lees, Mario Gaudino, Vipin Zamvar, Andrzej Bochenek, Brian Buxton, Cliff K. Choong, Stephen Clark, Marek Deja, Jatin Desai, Ragheb Hasan, Marek Jasiński, Peter O’Keefe, Fernando Moraes, John Pepper, Siven Seevanayagam, C. Sudarshan, Uday Trivedi, Stanisław Woś, John D. Puskas, Marcus Flather

New England Journal of Medicine · 2019

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Summary

BACKGROUND: Multiple arterial grafts may result in longer survival than single arterial grafts after coronary-artery bypass grafting (CABG) surgery. We evaluated the use of bilateral internal-thoracic-artery grafts for CABG. METHODS: We randomly assigned patients scheduled for CABG to undergo bilateral or single internal-thoracic-artery grafting. Additional arterial or vein grafts were used as indicated. The primary outcome was death from any cause at 10 years. The composite of death from any cause, myocardial infarction, or stroke was a secondary outcome. RESULTS: A total of 1548 patients were randomly assigned to undergo bilateral internal-thoracic-artery grafting (the bilateral-graft group) and 1554 to undergo single internal-thoracic-artery grafting (the single-graft group). In the bil

Subject
Other / interdisciplinary
Source type
Peer-reviewed study
System type
Other
DOI
10.1056/nejmoa1808783
Catalogue ID
SNmojj22ai-750qdr
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