Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Antiplatelet therapy after coronary artery bypass surgery: five year follow-up of randomised DACAB trial

Yunpeng Zhu, Wei Zhang, Arnaldo Dimagli, Lin Han, Zhaoyun Cheng, Ju Mei, Xin Chen, Xiaowei Wang, Yanzai Zhou, Qing Xue, Junlong Hu, Min Tang, Rui Wang, Yuanyuan Song, Lei Kang, Björn Redfors, Mario Gaudino, Qiang Zhao

BMJ · 2024

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Summary

OBJECTIVE: To assess the effect of different antiplatelet strategies on clinical outcomes after coronary artery bypass grafting. DESIGN: Five year follow-up of randomised Different Antiplatelet Therapy Strategy After Coronary Artery Bypass Grafting (DACAB) trial. SETTING: Six tertiary hospitals in China; enrolment between July 2014 and November 2015; completion of five year follow-up from August 2019 to June 2021. PARTICIPANTS: 500 patients aged 18-80 years (including 91 (18.2%) women) who had elective coronary artery bypass grafting surgery and completed the DACAB trial. INTERVENTIONS: Patients were randomised 1:1:1 to ticagrelor 90 mg twice daily plus aspirin 100 mg once daily (dual antiplatelet therapy; n=168), ticagrelor monotherapy 90 mg twice daily (n=166), or aspirin monotherapy 100

Subject
Other / interdisciplinary
Source type
Peer-reviewed study
System type
Other
DOI
10.1136/bmj-2023-075707
Catalogue ID
SNmojj23mv-304v1d
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