Summary
This review consolidates current knowledge on milk-derived extracellular vesicles, focusing on isolation and characterisation methodologies essential for functional and omics studies. The paper synthesises evidence demonstrating that milk-derived EVs carry bioactive molecules (proteins, lipids, nucleic acids) and mediate inter-cellular signalling, with established roles in immune regulation and intestinal development. The authors argue that rigorous selection of isolation and characterisation methods is prerequisite for downstream research and development of these vesicles for application in infant nutrition and functional foods.
UK applicability
Findings on milk-derived EV isolation and characterisation are methodologically applicable to UK dairy research and infant formula development, particularly relevant to UK food safety and nutrition standards for functional foods. However, the abstract does not specify UK-specific regulatory or production contexts.
Key measures
Methods for EV isolation and characterisation; structural integrity and biological viability metrics; functional outcomes including immune regulation and intestinal development promotion
Outcomes reported
This review summarises isolation and characterisation methods for milk-derived extracellular vesicles (EVs) and their biological functions. The paper synthesises evidence on the roles of milk-derived EVs in immune regulation and intestinal development, and their potential applications in infant formula and functional food development.
Topic tags
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