Pulse Brain · Growing Health Evidence Index
Tier 1 — Meta-analysis / systematic reviewPeer-reviewed

Hormetic dose responses induced by organic flame retardants in aquatic animals: Occurrence and quantification

Tao Sun, Chenglong Ji, Fei Li, Huifeng Wu

The Science of The Total Environment · 2022

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Summary

This paper investigates hormetic dose responses—characterised by low-dose stimulation and high-dose inhibition—induced by organic flame retardants in aquatic fauna. As suggested by the title and journal scope, the authors appear to have quantified the occurrence and magnitude of these non-monotonic responses, contributing to understanding of how aquatic organisms respond to contaminant exposure across dose ranges. The work may inform risk assessment frameworks by documenting dose thresholds below which apparent adaptive or stimulatory effects occur.

UK applicability

Findings are relevant to UK water quality monitoring and regulatory frameworks for synthetic chemicals in aquatic environments, particularly as organic flame retardants are widely used in consumer products and building materials. The hormetic response characterisation could inform UK and EU chemical safety assessment standards if similar effects are documented in native freshwater and marine species.

Key measures

Hormetic dose–response curves; threshold concentrations; effect magnitudes in aquatic animal models

Outcomes reported

The study examined dose–response relationships induced by organic flame retardants in aquatic animals, with a focus on identifying and quantifying hormetic (non-monotonic) responses. The research appears to have characterised the occurrence and magnitude of beneficial low-dose effects of these contaminants.

Theme
Measurement & metrics
Subject
Pesticides, contaminants & food safety
Study type
Research
Study design
Systematic review or laboratory experimental study
Source type
Peer-reviewed study
Status
Published
System type
Aquaculture
DOI
10.1016/j.scitotenv.2022.153295
Catalogue ID
SNmok3j1zg-5joc7x

Topic tags

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