Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

Improvement in patient-reported outcomes after lung transplantation is not impacted by the use of extracorporeal membrane oxygenation as a bridge to transplantation

Nicholas A. Kolaitis, Allison Soong, Pavan Shrestha, Hanjing Zhuo, John Neuhaus, Patti P. Katz, John R. Greenland, Jeffrey A. Golden, Lorriana E. Leard, Rupal Shah, Steven R. Hays, Jasleen Kukreja, Mary Ellen Kleinhenz, Paul D. Blanc, Jonathan P. Singer

Journal of Thoracic and Cardiovascular Surgery · 2018

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Summary

This observational cohort study evaluated whether the use of extracorporeal membrane oxygenation as a bridge to lung transplantation affects the magnitude of improvement in patient-reported outcomes postoperatively. As suggested by the title, the analysis indicated that ECMO bridging status did not significantly impact the trajectory of patient-reported quality-of-life improvements following successful transplantation, suggesting that bridge-to-transplant strategy may not compromise functional recovery.

UK applicability

Findings are relevant to UK transplant centres performing lung transplantation and using ECMO bridging protocols, though applicability depends on similar patient selection criteria and postoperative management protocols in NHS transplant units.

Key measures

Patient-reported outcome measures (PROM) before and after transplantation; functional status and quality of life assessments

Outcomes reported

The study assessed changes in patient-reported quality of life and functional outcomes after lung transplantation, comparing recipients who received extracorporeal membrane oxygenation (ECMO) as a bridge to transplantation with those who did not.

Theme
General food systems / other
Subject
Other / interdisciplinary
Study type
Research
Study design
Observational cohort
Source type
Peer-reviewed study
Status
Published
Geography
United States
System type
Human clinical
DOI
10.1016/j.jtcvs.2018.01.101
Catalogue ID
SNmotmphoy-w7jioj

Topic tags

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