Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

Synthetic biology tools for environmental protection

Javad Aminian-Dehkordi, Shadi Rahimi, Mehdi Golzar-Ahmadi, Amritpal Singh, Javiera López, Rodrigo Ledesma‐Amaro, Ivan Mijakovic̀

Biotechnology Advances · 2023

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Summary

This narrative review examines how synthetic biology is expanding beyond microbial cell factories to address direct environmental protection challenges. The authors highlight remediation strategies based on genetically engineered microbes and plants capable of sensing and responding to specific pollutants from industrial and agricultural sources, alongside computational approaches that facilitate tool design and application. The work reflects a broader shift in synthetic biology from renewable chemical production toward active ecosystem restoration and contaminant management.

UK applicability

The synthetic biology remediation approaches discussed may be applicable to UK environmental policy and land management, particularly for addressing agricultural and industrial pollutants. However, regulatory frameworks for releasing genetically modified organisms into UK ecosystems remain restrictive, which may limit near-term practical deployment of engineered microbial and plant-based solutions.

Key measures

Not applicable — this is a review article synthesising existing approaches and technologies rather than reporting original measurements

Outcomes reported

The review synthesises synthetic biology approaches for environmental protection, focusing on remediation systems using genetically engineered microbes and plants to sense and respond to pollutants. It presents an overview of computational tools that support the design and application of synthetic biology in environmental contexts.

Theme
Climate & resilience
Subject
Pesticides, contaminants & food safety
Study type
Narrative Review
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Laboratory / in vitro
DOI
10.1016/j.biotechadv.2023.108239
Catalogue ID
SNmov5itu0-j0lh75

Topic tags

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