Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

Hyperthermophilic Composting Accelerates the Removal of Antibiotic Resistance Genes and Mobile Genetic Elements in Sewage Sludge

Hanpeng Liao, Xiaomei Lü, Christopher Rensing, Ville‐Petri Friman, Stefan Geisen, Zhi Chen, Zhen Yu, Zhong Wei, Shungui Zhou, Yong‐Guan Zhu

Environmental Science & Technology · 2017

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Summary

This study compared hyperthermophilic composting with conventional composting for treatment of sewage sludge as a fertiliser feedstock, focusing on the removal of antibiotic resistance genes and mobile genetic elements that pose public health risks. Hyperthermophilic composting achieved significantly higher removal rates (89% for ARGs, 49% for MGEs) with shorter half-lives than conventional composting. The mechanisms of removal differed by temperature: reduction of mobile genetic elements was the primary driver in hyperthermophilic composting, whilst changes in bacterial community composition were key in conventional composting.

UK applicability

This research is directly applicable to UK sewage sludge management and agricultural reuse policy. Given the UK's reliance on sludge application to agricultural land as a fertiliser and soil conditioner, implementing hyperthermophilic composting protocols could reduce the transmission pathway of antibiotic resistance genes to the food system and environment.

Key measures

ARG and MGE removal efficiency (%), half-lives of ARGs and MGEs (%), bacterial abundance and diversity, bacterial community composition

Outcomes reported

The study measured the removal efficiency of antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs) in sewage sludge under hyperthermophilic versus conventional composting conditions, and identified the underlying microbial mechanisms driving ARG and MGE reduction in each composting method.

Theme
Farming systems, soils & land use
Subject
Antimicrobial resistance
Study type
Research
Study design
Field trial / Comparative experimental study
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Food supply chain
DOI
10.1021/acs.est.7b04483
Catalogue ID
SNmov5kgcw-29tmkm

Topic tags

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