Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

Fibre impact on gut microbiota

Makki, K. et al.

2018

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Summary

This review, published in Cell Host & Microbe, synthesises evidence on how dietary fibre shapes the gut microbiome and influences host physiology, with particular attention to the production of short-chain fatty acids such as butyrate, propionate, and acetate. The authors likely discuss how fibre type, source, and fermentability determine the degree and nature of microbiota modulation. The paper represents a significant reference point in understanding diet–microbiome–host interactions and their implications for metabolic and immune health.

UK applicability

The findings are broadly applicable to UK dietary and public health policy, particularly in the context of low population fibre intake and NHS guidance on diet-related non-communicable diseases. UK researchers and dietitians can draw on this work to support recommendations for increased and diversified fibre consumption.

Key measures

Gut microbiota composition; short-chain fatty acid (SCFA) production; fibre fermentability; microbiome diversity indices; host immune and metabolic markers

Outcomes reported

The paper examines how different types of dietary fibre influence gut microbiota composition, microbial metabolite production (particularly short-chain fatty acids), and downstream effects on host immune and metabolic health. It likely reviews evidence across both experimental and observational studies.

Theme
Nutrition & health
Subject
Gut microbiome & dietary fibre
Study type
Narrative Review
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Human clinical
Catalogue ID
XL0386

Topic tags

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