Pulse Brain · Growing Health Evidence Index
Tier 2 — RCT / large cohortPeer-reviewed

Resistant starch modulates human microbiome

Martinez, I. et al.

2013

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Summary

This paper, published in PLoS ONE in 2013, investigates the modulatory effects of resistant starch on the human gut microbiome using a controlled dietary intervention. The authors likely employed high-throughput sequencing to characterise microbial community shifts in response to differing levels of resistant starch consumption. The findings are likely to suggest that resistant starch selectively promotes the growth of certain saccharolytic bacteria, with potential implications for colonic health and metabolic function.

UK applicability

Whilst the study was likely conducted in the United States, the mechanistic findings regarding resistant starch and gut microbiome modulation are broadly applicable to UK populations and are relevant to UK dietary guidelines on fibre intake and gut health research priorities.

Key measures

Gut microbiota composition (16S rRNA sequencing); bacterial taxon relative abundance; short-chain fatty acid concentrations; dietary resistant starch intake (g/day)

Outcomes reported

The study examined how dietary consumption of resistant starch alters the composition and functional capacity of the human gut microbiome. It likely reported changes in relative abundance of specific bacterial taxa and associated metabolic outputs such as short-chain fatty acid production.

Theme
Nutrition & health
Subject
Gut microbiome & dietary fibre
Study type
Research
Study design
RCT
Source type
Peer-reviewed study
Status
Published
Geography
United States
System type
Human clinical
Catalogue ID
XL0971

Topic tags

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