Pulse Brain · Growing Health Evidence Index
Tier 1 — Meta-analysis / systematic reviewPeer-reviewed

Association between pesticide exposure and childhood asthma: meta-analysis

Chen, C. et al.

2022

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Summary

This meta-analysis, published in Environmental Research in 2022, synthesises epidemiological evidence on the relationship between pesticide exposure and asthma development in children. By pooling data across multiple studies, it likely demonstrates a statistically significant elevated risk of childhood asthma among those exposed to pesticides, though the magnitude and certainty of effect may vary by pesticide type and exposure pathway. The findings contribute to growing evidence linking agricultural and residential pesticide use to childhood respiratory morbidity.

UK applicability

Although the study is international in scope, the findings are broadly applicable to the UK context, where pesticide use in agriculture and residential settings is regulated under UK REACH and the National Action Plan for the Sustainable Use of Pesticides; the evidence may inform ongoing UK policy debates around pesticide reduction targets and child health protections.

Key measures

Pooled odds ratio or relative risk for childhood asthma associated with pesticide exposure; heterogeneity statistics (I²); subgroup analyses by pesticide class or exposure route where available

Outcomes reported

The study assessed the association between exposure to pesticides (likely including organophosphates, pyrethroids, and other classes) and the incidence or prevalence of asthma in children. Pooled risk estimates such as odds ratios or relative risks across multiple epidemiological studies were reported.

Theme
Nutrition & health
Subject
Pesticides & human health
Study type
Meta-analysis
Study design
Meta-analysis
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Human clinical
Catalogue ID
XL0594

Topic tags

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