Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

The unexplored diversity of rough-seeded lupins provides rich genomic resources and insights into lupin evolution

Karolina Susek, Leonardo Vincenzi, Magdalena Tomaszewska, Magdalena Kroc, Edoardo Franco, Emanuela Cosentino, Antonina Rita Limongi, Umesh Kumar Tanwar, Humaira Jamil, Matthew N. Nelson, Philipp E. Bayer, David Edwards, Roberto Papa, Massimo Delledonne, Scott A. Jackson

Nature Communications · 2025

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Summary

This paper presents high-quality genome assemblies for two wild and partially domesticated rough-seeded lupin species adapted to drought-prone environments. The authors demonstrate that both L. cosentinii and L. digitatus are tetraploids with distinctive repetitive DNA profiles compared to cultivated lupin crops, and describe the complex evolutionary history involving polyploidization and rediploidization within the genus. These genomic resources provide a foundation for identifying and exploiting genetic variation to improve lupin crops for nutritional value, climate resilience and sustainable agriculture.

Regional applicability

Whilst the study focuses on Mediterranean and pan-Saharan lupin species, the genomic tools and evolutionary insights may inform lupin breeding programmes in the United Kingdom and northern Europe, particularly for developing climate-resilient protein crops. However, direct transferability depends on the relevance of drought-adaptation traits to UK growing conditions and crop breeding priorities.

Key measures

Genome assemblies; tetraploid chromosome configurations; repetitive DNA content characterisation; comparative genomic analysis across lupin species

Outcomes reported

The study reports genome assemblies of two rough-seeded lupin species (Lupinus cosentinii and L. digitatus) and characterises their tetraploid nature, repetitive DNA content, and evolutionary processes. These genomic resources are intended to enable systematic analysis of lupin diversity for crop improvement and sustainable agriculture.

Theme
Climate & resilience
Subject
Cereals & grains
Study type
Research
Study design
Laboratory / genomic analysis
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Arable cereals
DOI
10.1038/s41467-025-58531-w
Catalogue ID
SNmomgycxv-rw8zs1

Topic tags

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