Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

Transcatheter Therapy for the Tricuspid Valve: A Focused Review of Edge-to-Edge Repair and Orthotopic Valve Replacement

Mahesh V. Madhavan, Vratika Agarwal, Rebecca T. Hahn

Current Cardiology Reports · 2024

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Summary

This focused review examines two transcatheter approaches to treating severe tricuspid regurgitation: transcatheter edge-to-edge repair (T-TEER) and orthotopic transcatheter tricuspid valve replacement (TTVR). The authors synthesise recent clinical evidence, including the TRILUMINATE randomised trial, and provide a technical and anatomical framework to guide device selection. The review highlights that whilst T-TEER safely reduces regurgitation and improves health status, orthotopic TTVR shows promise for more complete tricuspid regurgitation elimination.

Regional applicability

Both T-TEER and TTVR are approved in Europe and the USA, making findings relevant to United Kingdom interventional cardiology practice. However, as this is a clinical cardiology review without agricultural or nutritional focus, its applicability to UK farming systems or food policy is not established.

Key measures

Tricuspid regurgitation reduction; health status outcomes; clinical efficacy; anatomic suitability for device selection

Outcomes reported

The review evaluates transcatheter tricuspid valve interventions (T-TEER and orthotopic TTVR) for treating severe tricuspid regurgitation, examining technical features, anatomic limitations, clinical data, and offering a framework for device selection.

Theme
Nutrition & health
Subject
Out of scope / non-food
Study type
Narrative Review
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
Geography
United States
System type
Human clinical
DOI
10.1007/s11886-024-02051-4
Catalogue ID
SNmpeyuob4-8cb8rq

Topic tags

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