Summary
This nationwide Dutch registry study examined 12,822 patients with prior coronary artery bypass surgery who underwent repeat percutaneous coronary intervention between 2017 and 2021. Isolated native vessel interventions were performed in 75.2% of cases, whilst acute coronary syndrome presentation was strongly associated with bypass graft interventions. At one-year follow-up, interventions including bypass grafts showed higher rates of major adverse cardiac events (19.7% versus 14.3%), driven primarily by target vessel revascularisation rather than mortality differences.
Regional applicability
This study was conducted in the Netherlands and reports outcomes from a nationwide Dutch registry. Findings regarding clinical decision-making between native vessel and graft intervention in post-CABG patients may be broadly applicable to United Kingdom practice given similar healthcare systems and revascularisation protocols, though UK-specific registry data would be needed to confirm transferability to the National Health Service context.
Key measures
Major adverse cardiac events (all-cause death and target vessel revascularisation at one year); 30-day composite of all-cause death, myocardial infarction, and target vessel revascularisation; association of acute coronary syndrome presentation with graft intervention choice
Outcomes reported
The study compared major adverse cardiac events (MACE) at one year post-PCI between isolated native vessel interventions and those including bypass grafts in patients with prior CABG. Secondary outcomes included 30-day composite of all-cause death, myocardial infarction, and target vessel revascularisation.
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