Summary
This meta-analysis of 14 studies (12 observational, 2 RCTs) comprising 4226 patients compared hybrid coronary revascularization with conventional CABG for multivessel coronary artery disease. HCR showed comparable long-term mortality and MACCE rates but demonstrated advantages in perioperative outcomes including reduced blood transfusion, shorter hospital stays, and lower acute kidney injury risk. However, CABG was associated with lower rates of long-term repeat revascularisation, suggesting trade-offs in patient selection between techniques.
Regional applicability
This is a meta-analysis of international published data with no specified geographic restriction, so findings are broadly applicable to United Kingdom cardiac practice. The transferability depends on whether UK patient populations, surgical techniques, and post-operative protocols align with those in the included studies, which likely represent mixed European and North American centres.
Key measures
5-year mortality (odds ratio), long-term MACCE (odds ratio), perioperative blood transfusion (odds ratio), mean hospital stay (weighted mean difference), postoperative acute kidney injury (odds ratio), long-term repeat revascularization (odds ratio)
Outcomes reported
The study compared five-year mortality, major adverse cardiac and cerebral events (MACCE), perioperative blood transfusion, hospital stay length, acute kidney injury, and repeat revascularization rates between hybrid coronary revascularization and traditional CABG.
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