Summary
This expert opinion paper reviews the integration of medical therapy and percutaneous interventional procedures in managing valvular heart disease complicated by heart failure. Rather than the traditional sequential approach, the authors argue for a more integrated strategy that exploits synergistic effects between guideline-directed medical therapy and intervention to improve patient tolerability, quality of life and clinical outcomes, with coverage of secondary mitral regurgitation, aortic stenosis and regurgitation, and tricuspid regurgitation.
Regional applicability
The paper addresses clinical management strategies applicable across high-income healthcare systems, including the United Kingdom. The evolving role of percutaneous interventions in high-risk patients reflects contemporary European and international practice patterns that are increasingly adopted in UK NHS cardiology centres.
Key measures
Clinical outcomes, quality of life, tolerability and efficacy of combined medical and percutaneous interventional approaches in valvular heart disease with coexistent heart failure
Outcomes reported
The paper summarises current evidence and evolving clinical practices for integrated management of valvular heart disease in heart failure patients, examining synergistic effects of medical and interventional therapies across multiple valve lesions.
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