Summary
This narrative review examines tricuspid regurgitation (TR) as a serious complication of cardiac implantable electronic devices (CIEDs), which are essential for managing arrhythmias and preventing sudden cardiac death. The authors highlight that whilst CIEDs are lifesaving, device-related TR is independently associated with increased mortality and heart failure hospitalisation, yet management options remain limited once significant TR develops. The review emphasises the need for careful patient selection and innovative implantation strategies to balance the therapeutic benefits of CIEDs against the risk of iatrogenic TR.
Regional applicability
This is a clinical cardiology review with no specific geographic focus; findings on device-related TR and management challenges are broadly applicable to United Kingdom clinical practice where CIEDs are widely implanted. Transferability is high as the physiological mechanisms and clinical outcomes are device- and anatomy-dependent rather than population-specific.
Key measures
Mortality risk, heart failure hospitalisation risk, tricuspid regurgitation severity and prevalence
Outcomes reported
The review examines the clinical importance, mechanisms, and management challenges of lead-related tricuspid regurgitation (TR) in patients with cardiac implantable electronic devices (CIEDs). TR associated with CIEDs is identified as independently associated with increased mortality and higher risk of heart failure hospitalisation.
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