Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Metal Ions, Metal Chelators and Metal Chelating Assay as Antioxidant Method

İlhami Gülçın; Saleh Alwasel

Processes · 2022

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Summary

Heavy metals are essential for a wide range of biological processes, including the growth and reproduction of cells, synthesis of biomolecules, many enzymatic reactions, and the body’s immunity, but their excessive intake is harmful. Specifically, they cause oxidative stress (OS) and generate free radicals and reactive oxygen species (ROS) in metabolism. In addition, the accumulation of heavy metals in humans can cause serious damage to different organs, especially respiratory, nervous and reproductive and digestive systems. Biologically, metal chelation therapy is often used to treat metal toxicity. This process occurs through the interaction between the ligand and a central metal atom, forming a complex ring-like structure. After metals are chelated with appropriate chelating agents, the

Source type
Peer-reviewed study
DOI
10.3390/pr10010132
Catalogue ID
NRmo9rin9c-0zj
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