Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

The Safe and Effective Use of Plant-Based Diets with Guidelines for Health Professionals

Winston J. Craig; Ann Reed Mangels; Ujué Fresán; Kate Marsh; Fayth L. Miles; Angela Saunders; Ella Haddad; Celine Heskey; Patricia Johnston; Enette Larson‐Meyer; Michael J. Orlich

Nutrients · 2021

Read source ↗ All evidence

Summary

This narrative review synthesises scientific evidence demonstrating that plant-based diets (vegan and lacto-ovo-vegetarian) are safe and effective across all life stages, including pregnancy, lactation, childhood, and older age. The authors address key nutritional concerns including vitamin B12, calcium, vitamin D, iron, zinc, and omega-3 fatty acids, recommending use of fortified foods and supplements where appropriate. The review highlights disease-preventative mechanisms including high fibre and polyphenolic content associated with diverse gut microbiota and anti-inflammatory metabolites, and provides practical guidelines for health professionals.

Regional applicability

Although the review is global in scope, findings are directly applicable to United Kingdom practice and policy. The UK has increasing adoption of plant-based diets, and the nutrient guidance aligns with UK dietary standards and professional practice frameworks for registered dietitians and healthcare providers.

Key measures

Disease prevention and management (cardiovascular disease, cancer, diabetes, obesity, osteoporosis); nutrient intake and adequacy (vitamin B12, calcium, vitamin D, iron, zinc, omega-3 fats); gut microbiota composition; inflammatory markers

Outcomes reported

A systematic review of scientific evidence on plant-based diets' preventative and therapeutic roles in cardiovascular disease, cancer, diabetes, obesity, and osteoporosis across all life stages. The review synthesises evidence on safety, nutrient adequacy, and health outcomes, with recommendations for health professional guidance.

Theme
Nutrition & health
Subject
Dietary patterns & chronic disease
Study type
Narrative Review
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
Geography
Global
System type
Human clinical
DOI
10.3390/nu13114144
Catalogue ID
NRmsxs4hld-008

Topic tags

Pulse AI · ask about this record

Dig deeper with Pulse AI.

Pulse AI has read the whole catalogue. Ask about this record, its theme, or how the findings apply to UK farming and policy — every answer cites the underlying studies.