Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Genetics, epigenetics and transgenerational transmission of obesity in children

Nadia Panera, Claudia Mandato, Annalisa Crudele, S. Bertrando, Pietro Vajro, Anna Alisi

Frontiers in Endocrinology · 2022

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Summary

Sedentary lifestyle and consumption of high-calorie foods have caused a relentless increase of overweight and obesity prevalence at all ages. Its presently epidemic proportion is disquieting due to the tight relationship of obesity with metabolic syndrome and several other comorbidities which do call for urgent workarounds. The usual ineffectiveness of present therapies and failure of prevention campaigns triggered overtime a number of research studies which have unveiled some relevant aspects of obesity genetic and epigenetic inheritable profiles. These findings are revealing extremely precious mainly to serve as a likely extra arrow to allow the clinician's bow to achieve still hitherto unmet preventive goals. Evidence now exists that maternal obesity/overnutrition during pregnancy and l

Subject
Maternal, infant & child nutrition
Source type
Peer-reviewed study
System type
Other
DOI
10.3389/fendo.2022.1006008
Catalogue ID
SNmoj1yugd-vhipvs
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