Pulse Brain · Growing Health Evidence Index
Tier 1 — Meta-analysis / systematic reviewPeer-reviewed

Hybrid repair versus conventional open repair for thoracic aortic arch aneurysms

Ala Elhelali, Niamh Hynes, Declan Devane, Sherif Sultan, Edel P. Kavanagh, Liam Morris, Dave Veerasingam, Fionnuala Jordan

Cochrane Database of Systematic Reviews · 2021

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Summary

This Cochrane systematic review compares hybrid repair (combining supra-aortic vascular debranching with aortic arch stent grafting) against conventional open surgical repair for thoracic aortic arch aneurysms. The review addresses uncertainty about the short- and long-term safety and effectiveness of the hybrid technique, which has been proposed as a less invasive therapeutic alternative but carries technical challenges related to aortic arch angulation. The authors searched multiple databases through March 2021 to identify randomised controlled trials and controlled clinical trials comparing the two approaches.

Regional applicability

This systematic review is applicable to UK vascular surgery practice, where both hybrid and open repair techniques are available for managing thoracic aortic arch aneurysms. The findings would inform clinical guidelines and surgical decision-making across UK National Health Service vascular centres.

Key measures

The abstract does not specify the primary outcome measures. Based on the objectives, the review likely assessed mortality, major complications, technical success rates, and long-term durability of repairs.

Outcomes reported

The study aimed to assess the effectiveness and safety of hybrid repair (HR) compared to conventional open surgical repair (OSR) for treating thoracic aortic arch aneurysms. Outcomes would typically include short- and long-term mortality, morbidity, complications, and functional outcomes, though the abstract does not specify the primary outcomes measured.

Theme
General food systems / other
Subject
Other / interdisciplinary
Study type
Systematic Review
Study design
Systematic review
Source type
Peer-reviewed study
Status
Published
System type
Human clinical
DOI
10.1002/14651858.cd012923.pub2
Catalogue ID
SNmojj22m8-zu50vh

Topic tags

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