Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

Utilization of the microbiome in personalized medicine

Karina Ratiner, Dragos Ciocan, Suhaib K. Abdeen, Eran Elinav

Nature Reviews Microbiology · 2023

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Summary

This Nature Reviews Microbiology article, authored by leading microbiome researchers including Eran Elinav, examines the translation of microbiome science into personalised medicine. The review synthesises evidence on how microbiome profiling might inform individual-level clinical decision-making and discusses current applications, limitations, and future directions for microbiome-based therapeutics and diagnostics. As suggested by the journal and authorship, the paper addresses both mechanistic understanding and practical implementation challenges in moving microbiome research toward clinical utility.

Regional applicability

The review's frameworks for microbiome-informed personalised medicine are globally applicable and may inform future NHS commissioning and clinical guidelines around microbiome testing and intervention. However, implementation in the UK will require integration with existing health systems and regulatory approval pathways.

Key measures

Microbiome composition and function; clinical outcomes associated with microbiome-targeted interventions; personalization strategies in microbiome medicine

Outcomes reported

The study reviews approaches to utilising microbiome analysis for tailored clinical interventions and personalised medical management. It examines evidence and methodological frameworks for translating microbiome research into clinical practice.

Theme
Nutrition & health
Subject
Gut microbiome & human health
Study type
Narrative Review
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Human clinical
DOI
10.1038/s41579-023-00998-9
Catalogue ID
SNmojqlzzb-5g5bse

Topic tags

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