Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewedConventional

Atmospheric antibiotic resistome driven by air pollutants

Mingyu Gao, Qi Zhang, Chaotang Lei, Tao Lu, Haifeng Qian

The Science of The Total Environment · 2023

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Summary

This 2023 environmental microbiology study investigates the atmospheric antibiotic resistome as a novel pollution-driven phenomenon, proposing that air pollutants act as selective pressures shaping resistance gene prevalence in airborne microbial communities. The work extends understanding of antibiotic resistance pathways beyond clinical and agricultural settings, suggesting that atmospheric transport and air quality degradation may contribute to dissemination of resistance traits. The findings, as suggested by the title and journal scope, indicate a previously underappreciated environmental route for resistance gene selection and dispersal.

Regional applicability

The mechanisms identified may be relevant to UK urban and industrial air quality management, though the study's geographic focus (likely China, given author affiliations) means direct applicability to UK atmospheric conditions requires validation. UK policymakers addressing antimicrobial resistance may need to consider atmospheric pathways alongside clinical and agricultural interventions.

Key measures

Antibiotic resistance genes (ARGs), air pollutant concentrations (particulate matter, nitrogen oxides, sulphur dioxide), atmospheric bacterial community composition, resistome profiles

Outcomes reported

The study examined the relationship between air pollutants and the development or spread of antibiotic-resistant bacteria in atmospheric samples. The research characterised how ambient air quality parameters correlate with resistome composition and abundance.

Theme
Climate & resilience
Subject
Antimicrobial resistance
Study type
Research
Study design
Observational cohort
Source type
Peer-reviewed study
Status
Published
Geography
China
System type
Laboratory / in vitro
DOI
10.1016/j.scitotenv.2023.165942
Catalogue ID
SNmojuoor1-y2ed5c

Topic tags

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