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Tier 1 — Meta-analysis / systematic reviewPeer-reviewed

Global, regional, and national burden of asthma and atopic dermatitis, 1990–2021, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021

Jiyeon Oh, Soeun Kim, Min Seo Kim, Yohannes Abate, Samar Abd ElHafeez, Atef Abdelkader, Parsa Abdi, Deldar Morad Abdulah, Richard Gyan Aboagye, Hassan Abolhassani, Dariush Abtahi, Hasan Abualruz, Eman Abu‐Gharbieh, Salahdein Aburuz, Mesafint Molla Adane, Isaac Yeboah Addo, Olumide Thomas Adeleke, Bashir Aden, Qorinah Estiningtyas Sakilah Adnani, Saryia Adra, Muhammad U. Afzal, Sajjad Ahmad, Tauseef Ahmad, Ali Ahmadi, Syed Anees Ahmed, Salah Al Awaidy, Mohamad Anas Al Bakour, Khurshid Alam, Mohammed ALBashtawy, Ayman Al‐Eyadhy, Adel Al‐Gheethi, Fadwa Alhalaiqa, Syed Shujait Ali, Waad Ali, Sheikh Mohammad Alif, Samah W. Al‐Jabi, Jaber S. Alqahtani, Mohammad Alqudah, Ahmad Alrawashdeh, Najim Z. Alshahrani, Zaid Altaany, Awais Altaf, Ala’a B. Al‐Tammemi, Khalid A Altirkawi, Nelson Alvis‐Guzmán, Hassan Alwafi, Mohammad Al‐Wardat, Yaser Mohammed Al‐Worafi, Hany Aly, Mohammad S. Alyahya, Karem H. Alzoubi, Ganiyu Adeniyi Amusa, Adnan Ansar, Boluwatife Stephen Anuoluwa, Iyadunni Adesola Anuoluwa, Anayochukwu Edward Anyasodor, Jalal Arabloo, Aleksandr Y. Aravkin, Demelash Areda, Mohammad Asghari Jafarabadi, Tahira Ashraf, Seyyed Shamsadin Athari, Avinash Aujayeb, Lemessa Assefa A Ayana, Shahkaar Aziz, Ahmed Y. Azzam, Hiba Jawdat Barqawi, Amadou Barrow, Mohammad‐Mahdi Bastan, Kavita Batra, Priyamadhaba Behera, Payam Behzadi, Michelle L Bell, Alice A Beneke, Alemshet Yirga Berhie, Kebede Beyene, Priyadarshini Bhattacharjee, Jasvinder Singh Bhatti, Obasanjo Afolabi Bolarinwa, Souad Bouaoud, Yasser Bustanji, Nadeem Shafique Butt, Paulo Augusto Moreira Camargos, Luis Alberto Cámera, Andrea Carugno, Muthia Cenderadewi, Sonia Cerrai, Sandip Chakraborty, Jeffrey Shi Kai Chan, Rama Mohan Chandika, Vijay Kumar Chattu, Anis Ahmad Chaudhary, Esther Cheng, Fatemeh Chichagi, Ritesh Chimoriya, Patrick R Ching, Jesús Lorenzo Chirinos-Cáceres, Yuen Yu Chong, Hitesh Chopra, Dinh‐Toi Chu

The Lancet Respiratory Medicine · 2025

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Summary

This Global Burden of Disease Study 2021 systematically analysed the epidemiological burden of asthma and atopic dermatitis across 195 countries and territories from 1990 to 2021, integrating multi-source data to estimate disease prevalence, mortality, and disability impact. The analysis provides global and regional estimates stratified by demographic factors and extends projections to 2050 to inform health policy prioritisation and resource allocation in respiratory and dermatological disease management.

Regional applicability

As a global systematic analysis, findings are applicable to United Kingdom epidemiological surveillance and public health planning for asthma and atopic dermatitis. The study's country-level stratification permits comparison of United Kingdom burden trends against global and regional peers, supporting evidence-based allocation of National Health Service resources for these conditions.

Key measures

Disease prevalence, mortality, disability-adjusted life years (DALYs), stratified by age, sex, and sociodemographic index; burden projections to 2050

Outcomes reported

The study quantified the epidemiological burden of asthma and atopic dermatitis across 195 countries and territories from 1990 to 2021, including prevalence, mortality, and disability-adjusted life years (DALYs), with projections extended to 2050.

Theme
Measurement & metrics
Subject
Out of scope / non-food
Study type
Systematic Review
Study design
Systematic analysis / Meta-analysis
Source type
Peer-reviewed study
Status
Published
Geography
Global
System type
Human clinical
DOI
10.1016/s2213-2600(25)00003-7
Catalogue ID
SNmpdjw4th-ai16df

Topic tags

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