Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

Diversification of an emerging bacterial plant pathogen; insights from the global spread of <i>Xanthomonas euvesicatoria</i> pv. <i>perforans</i>

Sujan Timilsina, Fernanda Iruegas-Bocardo, Mustafa O. Jibrin, Anuj Sharma, Aastha Subedi, Amandeep Kaur, Gerald V. Minsavage, José C. Huguet‐Tapia, Jeannie M. Klein-Gordon, Pragya Adhikari, Tika B. Adhikari, Gabriella Cirvilleri, Laura Belen Tapia de la Barrera, Eduardo Bernal, Tom Creswell, Đoàn Thị Kiều Tiên, Teresa A. Coutinho, Daniel S. Egel, Rubén Felix-Gástelum, David M. Francis, Misrak Kebede, Melanie L. Lewis Ivey, Frank J. Louws, Laixin Luo, Elizabeth Maynard, Sally A. Miller, Nguyễn Thị Thu Ngà, Ebrahim Osdaghi, A. M. Quezado‐Duval, Rebecca Roach, Francesca Rotondo, Gail E. Ruhl, Vou Moses Shutt, Petcharat Thummabenjapone, Cheryl L. Trueman, Pamela D. Roberts, Jeffrey B. Jones, Gary E. Vallad, Erica M. Goss

bioRxiv (Cold Spring Harbor Laboratory) · 2024

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Summary

This study presents a global-scale genomic characterisation of Xanthomonas euvesicatoria pv. perforans, the dominant causal agent of bacterial spot in tomato, using genome sequences from 270 strains across 13 countries. The analysis reveals notable genetic diversity and population structure, with evidence of intercontinental dissemination through tomato seed production chains and ongoing evolution of the pathogen pangenome, including acquisition and loss of virulence-associated type III secreted effectors. The findings underscore the pathogen as a model for understanding emergence and diversification of recently evolved bacterial plant pathogens.

Regional applicability

The study is global in scope and does not report United Kingdom-specific data. However, the findings are relevant to UK horticulture as Xanthomonas spp. are regulated quarantine pathogens in European tomato production; understanding global population structure and virulence factor diversity informs risk assessment and management strategies for domestic production and seed imports.

Key measures

Whole-genome phylogenetic analysis, type III secreted effector (Xop) gene diversity, strain genetic relatedness across geographical regions

Outcomes reported

The study characterised genetic diversity and population structure of Xanthomonas euvesicatoria pv. perforans across 270 strains from 13 countries using whole-genome sequencing, and examined variation in type III secreted effectors in relationship to phylogenetic lineages.

Theme
Measurement & metrics
Subject
Pesticides, contaminants & food safety
Study type
Research
Study design
Comparative genomic analysis
Source type
Peer-reviewed study
Status
Preprint
Geography
Global
System type
Horticulture
DOI
10.1101/2024.03.22.585974
Catalogue ID
SNmpw4822d-85079s

Topic tags

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