Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

Bone Broth Benefits: How Its Nutrients Fortify Gut Barrier in Health and Disease

Ayah Matar, Nada Abdelnaem, M. Camilleri

Digestive Diseases and Sciences · 2025

Read source ↗ All evidence

Summary

This narrative review examines the nutrient profile of bone broth—notably glycine, proline, and trace minerals—and their proposed roles in maintaining intestinal barrier integrity across health and disease states. The authors critically evaluate the peer-reviewed evidence supporting widely circulated functional claims, identifying substantial gaps in rigorous characterisation of bioactive compounds and mechanistic substantiation. The review highlights the disconnect between popular assertions and current empirical support in the literature.

Regional applicability

The review addresses a widely consumed functional food with growing UK market presence and consumer interest, though the paper's mechanistic and compositional focus does not address UK-specific dietary patterns or regulatory framework. Findings may inform evidence-based messaging around bone broth in UK nutrition practice and policy.

Key measures

Nutrient composition (glycine, proline, minerals); intestinal barrier function markers; mechanistic pathways

Outcomes reported

The review synthesises evidence on bone broth's nutritional composition, particularly amino acids and minerals, and their proposed mechanisms for supporting intestinal barrier integrity. It critically appraises the empirical evidence underpinning popular functional health claims.

Theme
Nutrition & health
Subject
Food composition & nutrient databases
Study type
Narrative Review
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
System type
Food supply chain
DOI
10.1007/s10620-025-08997-x
Catalogue ID
SNmpyz6bn6-qk2mh1

Topic tags

Pulse AI · ask about this record

Dig deeper with Pulse AI.

Pulse AI has read the whole catalogue. Ask about this record, its theme, or how the findings apply to UK farming and policy — every answer cites the underlying studies.