Summary
This 2025 systematic review and dose–response meta-analysis synthesises observational studies examining the relationship between dietary inflammatory index (a nutrient-based scoring system reflecting pro- and anti-inflammatory food and nutrient patterns) and chronic kidney disease risk. The analysis quantifies the magnitude and shape of association between higher dietary inflammatory potential and CKD development across included cohorts. The findings may inform dietary guidance for CKD prevention, though conclusions are limited by the observational nature of included studies.
Regional applicability
The findings derive from a global synthesis of observational cohorts, so applicability to United Kingdom populations depends on the dietary patterns and healthcare contexts represented in the included studies. Dietary inflammatory index research has been conducted in high-income settings including Europe and North America; transferability to UK primary and secondary prevention of CKD would benefit from UK-specific cohort data.
Key measures
Dietary inflammatory index (DII) scores; chronic kidney disease incidence or prevalence; dose–response relationship parameters
Outcomes reported
The study synthesised observational evidence on the association between dietary inflammatory index scores and risk of chronic kidney disease development. A dose–response meta-analysis quantified the magnitude and shape of this relationship across included cohort studies.
Topic tags
Dig deeper with Pulse AI.
Pulse AI has read the whole catalogue. Ask about this record, its theme, or how the findings apply to UK farming and policy — every answer cites the underlying studies.