Summary
This narrative review examines microRNAs as emerging therapeutic targets for cardiovascular disease, synthesising evidence on their discovery, characterisation, and progression into preclinical and clinical testing. The authors discuss advances in microRNA identification and manipulation, alongside challenges and prospects for clinical translation in treating cardiovascular conditions where conventional pharmacotherapy has limitations.
Regional applicability
The review is a synthesis of international research on microRNA therapeutics and does not address UK-specific healthcare contexts, policy frameworks, or clinical practice guidelines. Findings may inform UK cardiovascular research and drug development pipelines but require contextualisation within the UK National Health Service and regulatory environment.
Key measures
Not applicable — narrative review of microRNA therapeutic development and clinical translation
Outcomes reported
The review summarises the current state of microRNAs as therapeutic targets in the cardiovascular system, including recent advances in identification, characterisation, manipulation and clinical translation.
Topic tags
Dig deeper with Pulse AI.
Pulse AI has read the whole catalogue. Ask about this record, its theme, or how the findings apply to UK farming and policy — every answer cites the underlying studies.