Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewedConventional

The effects of sub-chronic exposure of Wistar rats to the herbicide Glyphosate-Biocarb®

Benedetti, A. L., et al

Toxicology Letters · 2004

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Summary

This laboratory study investigated the sub-chronic toxicological effects of Glyphosate-Biocarb® herbicide in Wistar rats. As an animal toxicity study published in a specialist toxicology journal, it likely characterises dose-related physiological and pathological changes following repeated exposure. The findings contribute to the herbicide safety literature, though direct applicability to human dietary risk assessment requires further investigation.

Regional applicability

The study does not specify geographical origin. As a rat toxicity study, findings are relevant to global herbicide safety evaluation but do not directly address UK farming practices or dietary exposure. Applicability depends on whether glyphosate-Biocarb® formulation and exposure routes modelled in rats reflect UK agricultural use patterns and residue profiles in food.

Key measures

Organ weights, histopathology, biochemical parameters (inferred from typical sub-chronic toxicity protocols)

Outcomes reported

The study evaluated physiological and pathological effects of repeated glyphosate-Biocarb® exposure in Wistar rats over a sub-chronic exposure period. Measured outcomes likely included organ weights, histopathological changes, and biochemical markers of toxicity.

Theme
Pesticides, contaminants & food safety
Subject
Pesticides, contaminants & food safety
Study type
Research
Study design
Laboratory animal toxicity study
Source type
Peer-reviewed study
Status
Published
Geography
United Kingdom
System type
Laboratory / in vitro
DOI
10.1016/j.toxlet.2004.04.008
Catalogue ID
IRmqh57ll5-5371d9

Topic tags

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