Potential of plant polyphenols to combat oxidative stress and inflammatory processes in farm animals

Summary

This narrative review examines the potential of plant polyphenols as feed additives to combat oxidative stress and inflammation in farm animals, areas where such conditions significantly affect animal health and performance. The authors synthesise findings on polyphenol bioavailability and metabolism in pigs, poultry, and cattle, and present evidence from existing farm animal studies on effects on antioxidant defences and inflammatory processes. The review notes that whilst polyphenols show promise based on cell culture, rodent, and human research, investigations specifically in farm animals remain limited.

Regional applicability

The review's focus on pigs, poultry, and cattle encompasses livestock species commonly farmed in the United Kingdom. The findings on polyphenol feed supplementation as a tool to improve animal welfare and performance through reduced oxidative stress may be applicable to UK livestock production systems, though the review does not address UK-specific regulatory or economic contexts.

Key measures

Antioxidant system markers, inflammatory biomarkers, bioavailability and metabolism of polyphenols in farm animals

Outcomes reported

The review synthesises evidence on antioxidative and anti-inflammatory effects of plant polyphenols in pigs, poultry, and cattle. It examines polyphenol bioavailability, metabolism, and impacts on the antioxidant system and inflammatory markers in farm animal nutrition.

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