Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Bioavailability of Food Polyphenols: Current State of Knowledge

Gary Williamson

Annual Review of Food Science and Technology · 2025

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Summary

(Poly)phenols, including flavonoids, phenolic acids, and tannins, are a diverse class of compounds found in plant-based foods and beverages. Their bioavailability has been extensively described and detailed metabolic pathways elucidated. Although some parent (poly)phenols are absorbed intact in the small intestine, most pass to the colon where they are extensively catabolized and their microbial products absorbed into the circulation. The sum of the metabolites absorbed can reach almost 100% in some cases and in some individuals. In recent years, there have been three major areas of advancement: ( a ) comprehensive and systematic reviews have brought together bioavailability data, including detailed metabolic pathways in humans,

Source type
Peer-reviewed study
DOI
10.1146/annurev-food-060721-023817
Catalogue ID
NRmo3d4gae-0eb
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