Pulse Brain · Growing Health Evidence Index
Tier 1 — Meta-analysis / systematic reviewPeer-reviewedConventional

Agronomic Biofortification Strategies to Increase Grain Zinc Concentrations of Wheat, Rice and Maize: A Systematic Review and Network-Meta-Analysis.

Domingos IFN, Baranski M, Rengel Z, Bilsborrow P, Stewart G.

Campbell systematic reviews · 2026

Read source ↗ All evidence

Summary

This systematic review and network meta-analysis synthesises evidence from 44 field-based studies (27 wheat, 13 rice, 4 maize) to evaluate agronomic zinc biofortification strategies for increasing grain zinc concentrations in major staple cereals. The review compared multiple zinc fertilisation approaches—soil application, foliar application, and combined soil plus foliar methods—against control groups without zinc fertilisation. The findings provide comparative evidence on the relative effectiveness of different agronomic zinc biofortification methods for addressing micronutrient deficiency in developing countries.

Regional applicability

Whilst this global systematic review includes diverse agroclimatic and soil conditions, direct applicability to United Kingdom cereal production may be limited, as UK cereals typically serve feed and industrial rather than human nutrition markets. However, the methodological framework and comparative evidence on zinc fertilisation techniques could inform domestic soil health and crop nutrient density research.

Key measures

Grain zinc concentration (primary outcome) and grain yield (secondary outcome) across different zinc fertilisation application methods

Outcomes reported

The review evaluated the effectiveness of agronomic zinc biofortification strategies (soil, foliar, and combined applications) in increasing grain zinc concentrations and yield in wheat, rice, and maize through network meta-analysis of field trials.

Theme
Nutrition & health
Subject
Crop nutrient density & mineral composition
Study type
Systematic Review
Study design
Systematic review with network meta-analysis
Source type
Peer-reviewed study
Status
Published
Geography
Global
System type
Arable cereals
DOI
10.1177/18911803261435900
Catalogue ID
NRmu75e9u5-010

Topic tags

Pulse AI · ask about this record

Dig deeper with Pulse AI.

Ask about this record, its theme or its relevance to UK farming and policy. Pulse AI uses selected catalogue evidence and cites the sources it draws on.