Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

Type 2 diabetes mellitus and cardiometabolic outcomes in metabolic dysfunction-associated steatotic liver disease population

Nicholas Chew, Xin Pan, Bryan Chong, Chanchal Chandramouli, Mark Muthiah, Carolyn S.P. Lam

Diabetes Research and Clinical Practice · 2024

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Summary

This 2024 observational study quantifies the intersection of type 2 diabetes mellitus and metabolic dysfunction-associated steatotic liver disease (MASLD), characterising diabetes prevalence within MASLD cohorts and its associations with cardiometabolic outcomes. The work addresses an important epidemiological gap in understanding dual hepatic and metabolic dysfunction as a risk phenotype. Specific cardiometabolic effect estimates and clinical endpoints require confirmation from the full text.

Regional applicability

The study was conducted in a patient population with MASLD and type 2 diabetes; transferability to United Kingdom primary care and hepatology practice depends on patient demographics and healthcare system context, which are not specified in the available metadata. MASLD and type 2 diabetes comorbidity is increasingly prevalent in UK populations, making the risk stratification findings potentially applicable if the cohort characteristics align with UK patient populations.

Key measures

Diabetes prevalence in MASLD populations; cardiometabolic outcomes and risk factors (specific endpoints require full-text confirmation)

Outcomes reported

The study examined the prevalence of type 2 diabetes mellitus in populations with metabolic dysfunction-associated steatotic liver disease (MASLD) and quantified associations between diabetes status and cardiometabolic outcomes in this comorbid population.

Theme
Nutrition & health
Subject
Dietary patterns & chronic disease
Study type
Research
Study design
Observational cohort
Source type
Peer-reviewed study
Status
Published
System type
Human clinical
DOI
10.1016/j.diabres.2024.111652
Catalogue ID
SNmpdjw4th-k4vg18

Topic tags

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