Summary
This scoping review of 35 studies examined metallic nanoparticles used to combat Staphylococcus infections. Silver nanoparticles were the most frequently investigated, alongside copper, selenium, aluminium, gold, nickel, and vanadium nanoparticles. The review found copper and silver nanoparticles show promise against drug-resistant Staphylococcus aureus strains, though the authors note that standardisation and consistency in reporting methodology remain significant gaps in the research landscape.
Regional applicability
This is a laboratory-based nanotechnology review without geographic specificity. The findings are globally applicable in principle, though implementation of nanoparticle-based antimicrobial therapies in clinical or veterinary practice would depend on regulatory approval and clinical efficacy validation, which would be jurisdiction-specific.
Key measures
Zone of inhibition (mm); Minimum inhibitory concentration (µg/mL); Characterization methods (UV-visible spectroscopy, TEM, SEM, XRD)
Outcomes reported
The review identified seven types of metallic nanoparticles used against Staphylococcus infections, with silver nanoparticles being most commonly studied. Antimicrobial efficacy was evaluated using zone of inhibition (ZOI: 4.7–32 mm) and minimum inhibitory concentration (MIC: 0.25–3125 µg/mL).
Topic tags
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