Pulse Brain · Growing Health Evidence Index
Tier 1 — Meta-analysis / systematic reviewPeer-reviewedConventional

Empirical prediction of net portal appearance of volatile fatty acids, glucose, and their secondary metabolites (β-hydroxybutyrate, lactate) from dietary characteristics in ruminants: A meta-analysis approach1

Christelle Loncke, Isabelle Ortigues Marty, J. Vernet, H. Lapierre, D. Sauvant, Pierre Nozière

Journal of Animal Science · 2008

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Summary

This meta-analysis pooled data from the FLORA database of multi-catheterized ruminant studies to develop empirical prediction equations for nutrient absorption based on dietary characteristics and intake level. The authors derived robust models for volatile fatty acid production, glucose appearance, and secondary metabolite production that were valid for typical grazing and forage-based diets (≤30 g dry matter per kg body weight daily; <70 g concentrate per 100 g dry matter). The models offer a mechanistic foundation for nutrient-based energy feeding systems in ruminant nutrition.

Regional applicability

The meta-analytical approach draws on international data and is applicable to United Kingdom ruminant feeding systems, particularly those based on forage and pasture. The models' restriction to moderate concentrate levels and typical grazing intakes aligns well with UK grassland-based dairy and beef production, though validation on UK-specific herds and feeding regimens would strengthen local applicability.

Key measures

Net portal appearance (mmol/h per kg body weight) of total volatile fatty acids, individual VFA profiles (acetate, propionate, butyrate mol/100 mol), glucose, β-hydroxybutyrate, and lactate; adjusted R², residual mean square error; ruminally fermented organic matter intake; starch digestion in small intestine and rumen

Outcomes reported

The study developed and validated predictive equations for net portal appearance of volatile fatty acids, glucose, β-hydroxybutyrate, and lactate in ruminants based on dietary characteristics and intake level. Models explained 76–95% of variance in nutrient absorption across multiple ruminant studies.

Theme
Nutrition & health
Subject
Livestock nutrition & meat quality
Study type
Meta-analysis
Study design
Meta-analysis
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Pasture-based livestock
DOI
10.2527/jas.2008-0939
Catalogue ID
SNmv3cgxbc-96vmkg

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