Causal inference · Module 3: Getting an answer: study designs

The badger question: a UK case

How can one farming question get three different answers?

3.7 · 4 min 25 s · published

Each answer comes from a different design. A 1998–2005 trial found widespread badger culling cut cattle TB inside culled areas but raised it just outside. A difference-in-differences across 52 policy areas estimated a 56 per cent fall. A 2022 analysis by other methods found no clear effect. Ask: compared with what, who else was affected, and what exactly was done?

Key points

  • From 1998 to 2005, chance decided which of thirty areas got widespread culling, culling only near outbreaks, or none.
  • Widespread culling cut TB inside the culled areas but raised it on farms just outside: a spillover, at county scale.
  • A simple before and after can’t judge a policy when TB was already falling before it began.
  • The policy was a bundled treatment: its 56 per cent belongs to culling and extra cattle blood tests together.

Chapters

  1. 0:00 Recap: time zero
  2. 0:22 A British question
  3. 0:51 Ask with a trial
  4. 1:49 Ask with a comparison
  5. 2:52 What exactly was done?

Key terms

Randomisation
Letting chance decide which unit gets which treatment. Then no difference between units, known or unknown, can line up with the treatment except by luck, and statistics can say how big that luck might be. Ronald Fisher developed it for field trials at Rothamsted; it is the only method that handles confounders nobody has thought of.
Spillover (interference)
When one unit’s treatment changes another unit’s outcome. On farms, pests, pollinators, spray drift, water, disease and ideas cross the hedge: Bt maize cut corn borer numbers for neighbours who never planted it. Spillovers can be designed around with whole-area randomisation and buffer strips, or measured directly.
Staggered roll-out
When a change reaches different places or farms at different times, not all at once. Places that haven’t started yet can stand in for what would have happened without it, as long as early and late starters would otherwise have moved together. England’s badger control policy joined areas year by year from 2013.
Difference-in-differences
Comparing the change in a treated group with the change in a group that wasn’t treated, both measured before and after. If they were moving in parallel beforehand, the comparison group’s change shows what would have happened anyway, and the treated group’s extra change is the estimate. It rests on the parallel-trends assumption.
Parallel trends
The key assumption of difference-in-differences: without the change, the treated and comparison groups would have kept moving together. You can check whether they moved in parallel before the change, by tracking both groups over the earlier period, but not afterwards, so it always stays an assumption.
Bundled treatment
When what’s called a treatment is really several changes made together. A study can then say what the whole bundle did, but not which part did it. From 2017, most areas in England’s badger control policy also brought in extra blood tests for cattle, so the fall in TB belongs to culling and testing together.

Transcript

Last time's quick check: time zero is the moment each farm or person starts the treatment, or doesn't. Start everyone's clock at the same moment, or the comparison drifts. Bovine TB is one of the costliest problems in British cattle farming. Cattle that test positive are slaughtered, and the farm can't sell or move animals until it's clear.

Badgers can carry the infection too. So one question has divided farmers, scientists and the public for decades: does culling badgers cut TB in cattle? Here are three attempts to answer it. First, a randomised trial. From 1998 to 2005, thirty areas of English countryside were grouped in threes, and chance decided which area got widespread culling, which got culling only near outbreaks, and which got none.

Culling only near outbreaks seemed to make TB worse, and it was stopped. Widespread culling cut TB inside the culled areas, but while it went on, TB rose on farms just outside, probably because disturbed badgers roamed further. It's the spillover from film 3.5, at county scale.

From the first cull until the effect faded, cattle TB was about 29 per cent lower than in matched areas with no culling. Three years after culling stopped, the difference had gone. From 2013, culling became policy, in a staggered roll-out: areas joined year by year, where farmers applied, not where chance put them.

So a trial was no longer possible. A simple before and after won't do: in most of the worst-hit counties, TB was already falling before culling began. So in 2024, government scientists used difference-in-differences across 52 areas, comparing each area's change with areas that hadn't joined yet.

They estimated that herd TB fell by 56 per cent by the fourth year, somewhere between 41 and 69 per cent. Like every difference-in-differences, that rests on parallel trends: the assumption that, without the policy, the areas would have kept moving together. But what exactly was the treatment? From 2017, most cull areas also brought in extra blood tests for cattle, to find infected animals sooner. So this was a bundled treatment: that 56 per cent belongs to the whole policy, not to culling alone, and the authors say their analysis can't separate the parts.

A 2022 analysis of government data, using different methods, found no clear effect at all. One question, three answers. The lesson isn't to give up. It's to ask, every time: compared with what? Who else was affected? And what exactly was done? Those questions work just as well for a cover crop or a fertiliser plan. That completes the toolbox. Next, in Module 4: the machine-learning methods, in depth.

Questions

Why couldn’t a simple before and after tell whether the badger cull worked?

Because in most of the worst-hit counties, cattle TB was already falling before culling began, so a before-and-after would have credited the policy with a fall that was already under way. Only a comparison with areas that hadn’t yet joined could separate the two. That is what difference-in-differences does, provided the areas would otherwise have kept moving together.

What is a bundled treatment?

Several changes made together and called one treatment. From 2017, most areas in England’s badger control policy also brought in extra blood tests for cattle, so the estimated 56 per cent fall in herd TB belongs to the whole policy, not to culling alone, and the analysis can’t separate the parts. A farm that changes tillage, cover crops and grazing in one year has the same problem.

Sources

  1. Donnelly, C.A., Woodroffe, R., Cox, D.R. et al. (2003). Impact of localized badger culling on tuberculosis incidence in British cattle. Nature, 426(6968), 834–837. doi:10.1038/nature02192
  2. Donnelly, C.A., Woodroffe, R., Cox, D.R. et al. (2006). Positive and negative effects of widespread badger culling on tuberculosis in cattle. Nature, 439(7078), 843–846. doi:10.1038/nature04454
  3. Jenkins, H.E., Woodroffe, R. and Donnelly, C.A. (2010). The duration of the effects of repeated widespread badger culling on cattle tuberculosis following the cessation of culling. PLOS ONE, 5(2), e9090. doi:10.1371/journal.pone.0009090
  4. Langton, T.E.S., Jones, M.W. and McGill, I. (2022). Analysis of the impact of badger culling on bovine tuberculosis in cattle in the high-risk area of England, 2009–2020. Veterinary Record, 190(6), e1384. doi:10.1002/vetr.1384
  5. Birch, C.P.D., Bakrania, M., Prosser, A. et al. (2024). Difference in differences analysis evaluates the effects of the badger control policy on bovine tuberculosis in England. Scientific Reports, 14, 4849. doi:10.1038/s41598-024-54062-4

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