Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewedConventional

The Production of Malignant Primary Hepatic Tumours in the Rat by Feeding Dimethylnitrosamine

P N Magee; J M Barnes

British Journal of Cancer · 1956

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Key measures

Incidence and pathology of primary hepatic malignancies in rat livers following dimethylnitrosamine dietary administration

Outcomes reported

The study investigated whether feeding dimethylnitrosamine to rats induced malignant primary hepatic (liver) tumours. Tumour development and pathological characteristics were documented.

Theme
Nutrition & health
Subject
Pesticides, contaminants & food safety
Study type
Research
Study design
Laboratory animal feeding trial
Source type
Peer-reviewed study
Status
Published
Geography
United Kingdom
System type
Laboratory / in vitro
DOI
10.1038/bjc.1956.15
Catalogue ID
IRmqh56zun-a5a9ba

Topic tags

nitrosaminesfood safetyhepatic carcinogenesisdietary carcinogenstoxicologycontaminants
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