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Tier 1 — Meta-analysis / systematic reviewIndustry / policy reportConventional

Role played by the environment in the emergence and spread of antimicrobial resistance (AMR) through the food chain.

EFSA Panel on Biological Hazards (BIOHAZ), Koutsoumanis K, Allende A, Álvarez-Ordóñez A, Bolton D, Bover-Cid S, Chemaly M, Davies R, De Cesare A, Herman L, Hilbert F, Lindqvist R, Nauta M, Ru G, Simmons M, Skandamis P, Suffredini E, Argüello H, Berendonk T, Cavaco LM, Gaze W, Schmitt H, Topp E, Guerra B, Liébana E, Stella P, Peixe L.

EFSA J · 2021

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Summary

This EFSA Panel opinion synthesises evidence on how antimicrobial resistance emerges and propagates through environmental pathways linked to food production and the wider food chain. The assessment identifies soil, water, and manure as key environmental reservoirs and vectors, evaluating the relative risks posed by different agricultural systems and input practices. The work provides a comprehensive evidence base to inform policy on AMR mitigation across farming systems, food processing, and environmental management.

Regional applicability

The findings are directly applicable to UK agricultural policy, food safety regulation, and environmental protection frameworks, particularly given the UK's reliance on imported foodstuffs and the role of domestic intensive livestock farming. The evidence supports the UK's AMR strategy and the need for integrated surveillance and control measures across farm, food chain, and environmental compartments.

Key measures

Presence and prevalence of AMR bacteria and resistance genes in environmental matrices (soil, water, manure), food products, and livestock; pathways of transmission from agricultural use to human exposure

Outcomes reported

The study examined environmental routes through which antimicrobial resistance (AMR) emerges, persists, and spreads to human populations via the food chain, including soil, water, and agricultural inputs. It assessed the relative contribution of different food-producing sectors and environmental compartments to AMR transmission.

Theme
Policy, governance & rights
Subject
Antimicrobial resistance
Study type
Systematic Review
Study design
Systematic review
Source type
Policy report
Status
Published
Geography
Europe
System type
Food supply chain
DOI
10.2903/j.efsa.2021.6651
Catalogue ID
NRmo9rin9c-07i

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