Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

Reporting guidelines for human microbiome research: the STORMS checklist.

Mirzayi C, Renson A, Genomic Standards Consortium, Massive Analysis and Quality Control Society, Zohra F, Elsafoury S, Geistlinger L, Kasselman LJ, Eckenrode K, van de Wijgert J, Loughman A, Marques FZ, MacIntyre DA, Arumugam M, Azhar R, Beghini F, Bergstrom K, Bhatt A, Bisanz JE, Braun J, Bravo HC, Buck GA, Bushman F, Casero D, Clarke G, Collado MC, Cotter PD, Cryan JF, Demmer RT, Devkota S, Elinav E, Escobar JS, Fettweis J, Finn RD, Fodor AA, Forslund S, Franke A, Furlanello C, Gilbert J, Grice E, Haibe-Kains B, Handley S, Herd P, Holmes S, Jacobs JP, Karstens L, Knight R, Knights D, Koren O, Kwon DS, Langille M, Lindsay B, McGovern D, McHardy AC, McWeeney S, Mueller NT, Nezi L, Olm M, Palm N, Pasolli E, Raes J, Redinbo MR, Rühlemann M, Balfour Sartor R, Schloss PD, Schriml L, Segal E, Shardell M, Sharpton T, Smirnova E, Sokol H, Sonnenburg JL, Srinivasan S, Thingholm LB, Turnbaugh PJ, Upadhyay V, Walls RL, Wilmes P, Yamada T, Zeller G, Zhang M, Zhao N, Zhao L, Bao W, Culhane A, Devanarayan V, Dopazo J, Fan X, Fischer M, Jones W, Kusko R, Mason CE, Mercer TR, Sansone SA, Scherer A, Shi L, Thakkar S, Tong W, Wolfinger R, Hunter C, Segata N, Huttenhower C, Dowd JB, Jones HE, Waldron L.

Nat Med · 2021

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Summary

This paper presents STORMS, a multidisciplinary consensus-developed reporting checklist designed to standardise documentation of human microbiome research across epidemiology, laboratory procedures, bioinformatics and statistics. The tool addresses gaps in existing observational and genetic epidemiology guidelines by incorporating microbiome-specific reporting requirements. The checklist facilitates consistent manuscript preparation, peer review and comparative analysis across published microbiome studies.

Regional applicability

The STORMS checklist is a methodological standard of international applicability and will be directly relevant to United Kingdom-based microbiome researchers and journal editors. It supports rigorous, reproducible microbiome science regardless of geographic origin of research.

Key measures

17-item checklist with six sections covering methodological and analytical reporting elements for microbiome studies

Outcomes reported

Development and presentation of the STORMS (Strengthening The Organization and Reporting of Microbiome Studies) checklist, a 17-item standardised reporting tool for culture-independent human microbiome studies. The checklist organises reporting across six sections aligned with scientific publication structure, covering epidemiology, laboratory, bioinformatics and statistical analyses.

Theme
Measurement & metrics
Subject
Gut microbiome & human health
Study type
Guideline
Study design
Guideline
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Laboratory / in vitro
DOI
10.1038/s41591-021-01552-x
Catalogue ID
NRmu2mgrm0-034

Topic tags

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