Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

Revolution of Bioactive Compound Extraction: Impacts on Food Safety, Health, and Sustainability

Ahmed A. Zaky, Dorota Witrowa‐Rajchert, Małgorzata Nowacka

Food Safety and Health · 2025

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Summary

This narrative review synthesises current knowledge on extraction methods for plant bioactive compounds, contrasting traditional techniques (maceration, Soxhlet, heat reflux) with emerging sustainable approaches (supercritical fluid, ultrasound-assisted, microwave-assisted, and pulsed electric field extraction). The authors emphasise that innovative methods can minimise heat and solvent exposure, thereby preserving beneficial bioactive properties whilst addressing financial, technological, and regulatory barriers to implementation in food manufacturing.

Regional applicability

The review is not geographically specific and addresses extraction methodology applicable across jurisdictions. Findings on regulatory compliance and labelling transparency are relevant to United Kingdom food industry practices, though specific alignment with UK Food Standards Authority guidance would require supplementary assessment.

Key measures

Extraction efficiency, preservation of bioactive compounds (flavonoids, phenolic acids), heat exposure, solvent use, regulatory compliance, retention of antioxidant, anti-inflammatory, and antimicrobial properties

Outcomes reported

The review examines conventional extraction methods (heat reflux, maceration, Soxhlet) and innovative techniques (SFE, UAE, MAE, PEF) for isolating bioactive compounds from plant materials. It evaluates their principles, benefits, drawbacks, practical applications, and impacts on preservation of health-beneficial properties whilst meeting food safety and regulatory standards.

Theme
Nutrition & health
Subject
Food processing & bioavailability
Study type
Narrative Review
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
System type
Food supply chain
DOI
10.1002/fsh3.70012
Catalogue ID
SNmpyz6mgc-vvkva2

Topic tags

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