Summary
This European Hematology Association working group review synthesises current knowledge on iron deficiency and iron deficiency anaemia, addressing diagnosis, management, and prevention strategies. The paper acknowledges IDA as the most frequent haematological disorder in children globally (20–48% prevalence depending on region and age) and in women of reproductive age, and provides age- and gender-specific clinical recommendations to guide diagnosis and treatment.
Regional applicability
The recommendations are European consensus guidance and will be broadly applicable to United Kingdom clinical practice. The cited prevalence data (20.1% in children aged 0–4 years in industrialised countries) aligns with UK epidemiology, and the clinical approaches recommended reflect evidence-based international standards that inform NICE guidance and NHS policy.
Key measures
Haemoglobin concentration, haematocrit, erythrocyte morphology (microcytic, hypochromic), red blood cell count, plasma iron concentration, total body iron stores
Outcomes reported
The paper summarises evidence on the diagnosis, treatment, and prevention of iron deficiency (ID) and iron deficiency anaemia (IDA) across different population groups, and formulates clinical recommendations tailored by age, gender, and pregnancy status.
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