Perspective: Guiding Principles for the Implementation of Personalized Nutrition Approaches That Benefit Health and Function

Summary

This perspective paper, developed by a multidisciplinary panel convened by the International Life Sciences Institute's North American Branch, proposes the first formal definition of personalised nutrition and establishes 10 guiding principles to standardise implementation and establish credibility in an expanding field of commercially available PN programmes. The principles encompass user definition, validated methods, data quality, algorithm transparency, rigorous evidence, user accessibility, alignment with population recommendations, honest communication, and data protection. The authors identify critical barriers to broader acceptance, including definitional challenges around the health–disease continuum and gaps in biomarker science.

Regional applicability

Whilst developed by a North American body, the principles are presented as internationally applicable and would be relevant to UK policy-makers and health professionals developing PN guidance, particularly as the field of direct-to-consumer personalised nutrition services expands. The framework's emphasis on data privacy and regulatory clarity aligns with UK and European data protection requirements.

Key measures

Guiding principles framework; definition of personalised nutrition; identification of implementation challenges and barriers

Outcomes reported

The paper proposes a definition of personalised nutrition and establishes 10 guiding principles for implementation, intended to standardise evidence-based practice and establish credibility in PN approaches. The authors identify key challenges for wider adoption including biomarker identification, regulatory frameworks, accessibility, and outcome measurement.

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