Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewedConventional

Metabolic engineering of an alternative pathway for ascorbic acid biosynthesis in plants

Ashok Kumar Jain, Craig L. Nessler

Molecular Breeding · 2000

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Summary

This 2000 paper describes metabolic engineering strategies to introduce or enhance alternative biosynthetic pathways for ascorbic acid production in plants, with the goal of increasing vitamin C content in edible crops. The work represents early research in biofortification through molecular breeding techniques. The transferability to modern UK horticultural breeding and production depends on contemporary regulatory frameworks for genetically modified crops.

Regional applicability

Whilst this research addresses a global challenge in crop micronutrient density, the regulatory environment for genetically modified plants in the United Kingdom is restrictive, limiting direct application of transgenic approaches. The fundamental science on vitamin C biosynthesis pathways may inform conventional breeding or newer gene-editing strategies permissible under UK and EU law.

Key measures

Ascorbic acid (vitamin C) biosynthetic pathway genes and their expression; vitamin C accumulation in engineered plant tissues

Outcomes reported

The study reports on metabolic engineering approaches to enhance ascorbic acid (vitamin C) production in plants through alternative biosynthetic pathways. The work aimed to increase bioavailable micronutrient content in horticultural crops.

Theme
Nutrition & health
Subject
Micronutrient biofortification
Study type
Research
Study design
Laboratory / in vitro
Source type
Peer-reviewed study
Status
Published
Geography
United States
System type
Horticulture
DOI
10.1023/a:1009680818138
Catalogue ID
SNmvuhpzt0-hz1omy

Topic tags

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